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Featured Clinics
Spring Weight Loss & B12 Clinic
Spring, TX
(713) 493-0517
View Full ProfileKELM Wellness Evolution
Cypress, TX
(346) 377-5401
View Full ProfileGameday Men's Health Pearland
Pearland, TX
(281) 942-0196
View Full ProfileRenew Weight Loss
League City, TX
(832) 376-6996
View Full ProfileHouston Weight Loss Center - Webster
League City, TX
(281) 724-1901
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Medical Weight Loss Clinics in Houston
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64 clinics found in Greater Houston
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Medical Weight Loss in Houston, TX: GLP-1 Medications, Providers & What to Expect
Greater Houston has one of the largest and fastest-growing medical weight loss markets in Texas. Across Harris County, Fort Bend County, and Montgomery County, hundreds of physician-supervised clinics now offer FDA-approved GLP-1 receptor agonist medications, including semaglutide (Wegovy®, Ozempic®) and tirzepatide (Zepbound®, Mounjaro®), under board-certified medical oversight. Harris County's adult obesity rate exceeds 34%, among the highest in the state, making access to effective, physician-supervised programs a genuine public health priority for the Houston metro.
The Houston Weight Loss Directory lists verified, physician-supervised clinics across 22 Greater Houston communities, from Katy and Cypress in the west to Pearland and League City in the south, The Woodlands and Conroe in the north, and inner-loop neighborhoods including the Galleria area, River Oaks, The Heights, and Montrose. Every listing includes verified contact information, services offered, accepted insurance, and patient reviews so you can compare options before booking.
What is semaglutide? Semaglutide is a once-weekly injectable GLP-1 receptor agonist FDA-approved for chronic weight management (as Wegovy®, 2.4 mg) and type 2 diabetes (as Ozempic®). In the landmark STEP 1 clinical trial, patients lost an average of 14.9% of body weight over 68 weeks, results previously achievable only through bariatric surgery. Houston-area clinics offer both brand-name and compounded semaglutide programs, with pricing ranging from $199-$350/month for compounded to $1,300-$1,450/month for brand-name Wegovy without insurance.
What is tirzepatide (Mounjaro® / Zepbound®)? Tirzepatide is a newer dual GLP-1/GIP receptor agonist that has shown even stronger average weight loss results in clinical trials. The SURMOUNT-1 trial found patients on tirzepatide 15 mg lost an average of 22.5% of body weight over 72 weeks. Zepbound® is FDA-approved specifically for chronic weight management, while Mounjaro® is approved for type 2 diabetes. Both are now widely prescribed at Houston-area weight loss clinics in Katy, Sugar Land, The Woodlands, and Pearland.
Who qualifies? FDA approval criteria for Wegovy and Zepbound include adults with a BMI of 30 or higher (obesity), or 27 or higher with at least one weight-related condition such as type 2 diabetes, hypertension, high cholesterol, or sleep apnea. Houston physicians who specialize in obesity medicine conduct full metabolic workups, including lab panels, thyroid function, and cardiovascular risk assessment, before prescribing.
How much does it cost in Houston? Cost depends heavily on whether you use brand-name or compounded medication, and whether your insurance covers obesity treatment. Many Houston-area employer health plans now cover GLP-1 medications with prior authorization. Manufacturer savings programs from Novo Nordisk (Wegovy) and Eli Lilly (Zepbound) can reduce costs to $0-$25/month for eligible commercially insured patients. See our 2026 Houston pricing guide for a complete breakdown.
Featured Article
Semaglutide Cost in Houston 2026: $199-$1,500/mo Broken Down
Brand-name Wegovy runs $1,300-$1,500/month while compounded semaglutide from Houston clinics starts at $199. See the full cost breakdown and how to pay less.