Medical Weight Loss Clinics in Houston, TX
Houston has one of the highest concentrations of GLP-1 providers in Texas. Find a physician-supervised program in your neighborhood.
Houston is the largest city in Texas and one of the most medically diverse metros in the country. With 17 weight loss clinics spread across neighborhoods from The Heights to River Oaks, Montrose to Galleria, and Memorial to Spring Branch, most Houston residents have a quality GLP-1 provider within a few miles of home.
The city has seen rapid growth in physician-supervised weight loss programs over the past three years, driven by patient demand for semaglutide and tirzepatide, the GLP-1 receptor agonist medications that have produced clinically significant weight loss in large-scale trials. Houston-area providers range from dedicated weight loss practices to primary care clinics that have added GLP-1 programs, to med spas with physician oversight on staff.
The neighborhoods covered below span the inner loop, Galleria/Westheimer corridor, Heights and Washington Ave area, Memorial and West Houston, and the east and southeast sides. Whether you work in the Energy Corridor or Midtown, live in Montrose or Oak Forest, or are based anywhere across Harris County, there is likely a clinic close to your daily routine.
Clinics in Houston, TX
Featured spot available — only 1 clinic can be the sponsored provider for Houston.
Learn more →Clinic 45
Clinic 45 is a highly regarded medical weight loss clinic in Houston, offering physician-supervised programs including Semaglutide (Wegovy/Ozempic), Tirzepatide (Mounjaro/Zepbound), and comprehensive medical weight management. With early morning appointments available from 7 AM on Mondays, Clinic 45 makes it easy to prioritize your health around a busy schedule. Backed by an impressive 4.8-star rating across more than 1,366 Google reviews, Clinic 45 has built a strong reputation for delivering attentive, results-focused care to the Houston community.
Houston Weight Loss Center - Heights
Houston Weight Loss Center – Heights brings physician-supervised medical weight management to one of Houston's most vibrant neighborhoods. This established clinic offers cutting-edge GLP-1 therapies including Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro/Zepbound), tailored to each patient's individual health goals. With a strong reputation backed by nearly 280 patient reviews and a 4.7-star rating, the Heights location is a trusted choice for those seeking structured, medically guided weight loss support.
River Oaks Beauty and Weight Loss Center
Located in Houston's prestigious River Oaks area, River Oaks Beauty and Weight Loss Center offers a unique combination of physician-supervised medical weight loss and aesthetic services under one roof. The clinic provides evidence-based treatments including semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound), tailored to each patient's weight management goals. With a 4.8-star rating across 157 reviews, this dual-focus clinic is a trusted destination for patients seeking both lasting weight loss results and complementary aesthetic care.
Texas Weight Loss - Houston Southwest
Texas Weight Loss – Houston Southwest offers physician-supervised medical weight management in the heart of Southwest Houston. The clinic provides access to leading GLP-1 medications, including Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro/Zepbound), tailoring treatment plans to each patient's individual health goals. With early morning appointments available from 6 AM and a strong patient satisfaction record of 4.7 stars across nearly 400 reviews, this clinic delivers convenient, trusted care for lasting weight loss results.
Z Med Clinic and Med Spa - Greenbriar
Z Med Clinic and Med Spa – Greenbriar is a well-regarded multi-location medical wellness practice serving the Greenbriar/Midtown Houston area, offering a robust physician-supervised weight loss program centered on GLP-1 medications including Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro/Zepbound). Alongside medical weight management, the clinic provides hormone therapy and IV therapy, delivering a well-rounded approach to health and body optimization. With a strong patient satisfaction record reflected in nearly 600 reviews, Z Med Clinic combines the personalized care of a medical practice with the full-service experience of a modern med spa.
Woodforest Weight Loss
Woodforest Weight Loss is a physician-supervised medical weight loss clinic serving the East Houston and Woodforest community. The clinic offers a focused range of evidence-based treatments, including Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro/Zepbound), delivered through a comprehensive medical weight management program tailored to each patient's needs. With a strong 4.7-star rating across over 230 reviews, Woodforest Weight Loss has built a trusted reputation among Houston patients seeking effective, medically guided weight loss care.
Lifelong Weight Loss - Dr. Rupal Mathur MD
Lifelong Weight Loss is a physician-led medical weight loss practice near River Oaks, Houston, guided by Dr. Rupal Mathur, MD. The clinic offers personalized, physician-supervised weight management programs, including access to GLP-1 medications such as Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro/Zepbound). With a strong patient satisfaction rating, Dr. Mathur and her team are committed to supporting patients through every step of their weight loss journey with individualized, evidence-based care.
Houston Medical Wellness / Weight Loss Clinic
Houston Medical Wellness / Weight Loss Clinic is a physician-supervised weight loss practice conveniently located in Houston's prestigious Galleria area. The clinic offers a comprehensive suite of medical weight management solutions, including the latest GLP-1 receptor agonist therapies - Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro/Zepbound) - tailored to each patient's individual health goals. With a strong patient satisfaction record and accessible weekday hours beginning at 9 AM, this clinic provides a supportive, medically guided environment for sustainable weight loss.
Montrose Med Spa
Montrose Med Spa is a well-regarded medical spa in Houston's Montrose neighborhood offering physician-supervised weight loss with compounded semaglutide and tirzepatide. The clinic takes a personalized approach to appetite regulation and metabolic health, pairing GLP-1 therapy with aesthetic services in a welcoming, boutique setting. Open Tuesday through Saturday with flexible mid-week evening hours, it's convenient for patients living or working in Montrose, Midtown, Midtown, and the Upper Kirby area.
Relive Health - Houston Memorial
Relive Health's Houston Memorial location sits along the Katy Freeway near the Memorial Park area, offering physician-supervised medical weight loss with Semaglutide and Tirzepatide. As part of a national wellness network, Relive Health combines personalized GLP-1 treatment plans with IV therapy, hormone optimization, and other restorative wellness services. Open Tuesday through Saturday with Wednesday evening hours until 7 PM, the clinic serves patients across Memorial, River Oaks, the Energy Corridor, and West Houston.
Dream Aesthetics Med Spa
Dream Aesthetics Med Spa is a Houston Heights-adjacent clinic on Studemont Street offering semaglutide and tirzepatide weight loss programs alongside a full med spa menu. Their GLP-1 program combines appetite regulation, metabolic support, and aesthetic care under one roof. Open Monday through Saturday, the clinic is easily accessible from the Heights, Washington Avenue corridor, and Montrose.
Anuli Aesthetics & Weightloss
Anuli Aesthetics & Weightloss is located in the Galleria area of Houston, offering physician-supervised semaglutide weight loss programs with nutritionist consultations and ongoing patient support. Their approach combines GLP-1 therapy with personalized guidance to help patients achieve sustainable results. Located off Chimney Rock near the Galleria, the clinic is convenient for West Houston, Tanglewood, and Westheimer corridor patients.
LifeSculpt by ChristiMD
LifeSculpt by ChristiMD is a physician-led weight loss and longevity clinic on the Katy Freeway in West Houston, offering a structured 90-day weight loss transformation program built around GLP-1 therapy. The clinic provides semaglutide and tirzepatide injections alongside a full BioVitality program that addresses metabolic health, body composition, and long-term wellness. With a focus on lasting transformation rather than quick fixes, LifeSculpt serves patients across West Houston, Katy, and the Energy Corridor.
Huemn - M-K-T Heights
Huemn at M-K-T Heights brings functional medicine-based weight loss to the Houston Heights neighborhood, offering semaglutide from $99/month and tirzepatide from $199/month in a modern wellness environment. Their program integrates GLP-1 therapy with body composition tracking, biomarker testing, cryotherapy, and peptide-based support for a genuinely comprehensive approach to metabolic health. Located in the M-K-T development on North Shepherd, Huemn serves the Heights, Spring Branch, River Oaks, and Upper Kirby communities.
Houston Injection Medspa Bar
Houston Injection Medspa Bar is a Greenway Plaza-area med spa offering semaglutide and other injection-based wellness treatments in a relaxed, approachable setting. Their weekly semaglutide injection program is physician-supervised, with gradual dose titration and ongoing patient check-ins. Open Tuesday through Saturday with Saturday morning hours, the clinic serves patients from the Galleria, West University, River Oaks, and Greenway Plaza neighborhoods.
NeuMed Modern Urgent Care - Houston
NeuMed on Wirt Road is a modern urgent care and wellness clinic in the Spring Branch/Memorial area offering semaglutide and tirzepatide weight loss programs alongside urgent care, IV therapy, and other wellness services. Their GLP-1 programs are available in-clinic (weekly provider-administered injections) or at-home, with one of the more accessible entry-level price points in the Houston market. Open daily including evenings and weekends, NeuMed is one of the most convenient options for Houston patients with unpredictable schedules.
Houston Weight Loss Center - North Loop
Houston Weight Loss Center's North Loop location brings physician-supervised medical weight management to the Oak Forest and Garden Oaks area of Houston. Part of the established Houston Weight Loss Center network, this location offers semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound) as core treatment options, with a Monday through Friday schedule designed around working patients. The clinic serves North Houston patients seeking results-focused care without the commute to the Medical Center.
Why Houston Patients Are Choosing Local Medical Weight Loss Programs
Houston has one of the highest rates of obesity-related conditions in the country, and awareness of GLP-1 therapy has grown fast. Patients who previously managed weight through diet alone or with primary care guidance are increasingly seeking structured, physician-supervised programs that include baseline labs, a clear dose-escalation protocol, and regular follow-ups. Houston clinics offer the full range: from quick-start compounded semaglutide programs at 50-00 per month to comprehensive metabolic health programs coordinated alongside diabetes management, hormone therapy, or cardiovascular care.
Frequently Asked Questions
Which Houston neighborhoods have the most weight loss clinics?
The Heights, Galleria/Westheimer, Upper Kirby, Montrose, and Memorial are the most clinic-dense areas for medical weight loss inside the loop. West Houston and Spring Branch have solid options for residents on the west side. Patients in southeast, east, or southwest Houston have local options as well, though the density is lower and some residents find it worth driving to a nearby suburban clinic for more program variety.
Do Houston weight loss clinics accept insurance for semaglutide?
Yes. Most Houston clinics work with major commercial insurers including Blue Cross Blue Shield of Texas, Aetna, Cigna, and United. Prior authorization is required, and most plans require documented BMI of 30 or higher, or 27 with a weight-related comorbidity. Texas Medicaid does not broadly cover these medications for weight loss alone. Clinics vary in how much they assist with prior authorization, so ask upfront.
What is the cost of semaglutide in Houston without insurance?
Compounded semaglutide runs 50-50 per month at Houston clinics, depending on the neighborhood and program. Inner-loop providers tend to be priced slightly higher than suburban options. Brand-name Wegovy lists at ,300-,450 per month but is covered for many commercially insured patients. Novo Nordisk's NovoCare savings program can significantly reduce out-of-pocket costs for eligible patients.
What is the difference between a Houston weight loss clinic and a med spa offering semaglutide?
A medical weight loss clinic has a physician or licensed NP reviewing your labs and health history before prescribing, monitoring your progress, and adjusting your protocol over time. A med spa may offer semaglutide as an add-on service with less structured oversight. In Houston, many businesses blur this line, so ask specifically about the prescribing provider's credentials, whether labs are required, and what the follow-up protocol looks like.
Houston's size and medical infrastructure mean you have more options for physician-supervised weight loss than almost anywhere else in Texas. Use the directory to compare providers by neighborhood, read their service offerings, and call two or three before committing. The right program for you depends on your health history, schedule, and budget, and Houston has enough options to find a strong match.